Bioactive components have been isolated such as lignin,flavonoids, coumarins, steroids, terpenes, fatty acids, and aliphatic longchain compounds. Leucas aspera is known for its antiinflammatory, antithrombotic, antioxidant, anti carcinogenic properties 7 whereas cassia alata is known for its antifungal, laxative, purgative and antioxidant activity 11. In the present study, the antioxidant property of ethanolic extract of leucas aspera has been investigated. Different parts of this plant root, flower, leaf, stem have been found to have antioxidant, antibacterial and cytotoxic effect. In this formula k represents calyx, ccorolla, p perianth, aandroccium, ggynoecium. Plant tissue culture has paved way for the production of both pathogenfree plants and secondary metabolites in large scale. Neuropharmacological profile of methanolic extract of leucas. The relative density of weeds of cultivated fields were0. In vitro studies on antibacterial, antifungal, and cytotoxic properties of leucas aspera m akter1, mai khan2, mda muhsin1, k hamid3, m obayed ullah4, ij bulbul5, a firoz 1, m burhan uddin, kf urmi1 1department of pharmacy, jahangirnagar university, dhaka, bangladesh. The present investigation was aimed at evaluating the ethanol extract of leaves of leucas aspera has been found to possess antibacterial activity and antiinflammatory activity, cyclooxygenase cox, also called prostaglandin h synthase or pghs is a bifunctional enzyme exhibiting both cyclooxygenase and peroxidase activities. The plant is widely found in bangladesh and its bengali name is dondokolos.
The type of phytochemicals present in the extract was analyzed. Lamiaceae is an important medicinal plant in indigenous systems of medicine in india and commonly known as thumbai. Leucas aspera consists of phyto constituents which include. If the file has been modified from its original state, some details such as the timestamp may not.
In this work deals with the synthesis and characterization of silver nanoparticles using leucas aspera flower. In general, the crushed leaves of leucas species are applied to wounds, sores, especially those of the eyes and nose, chronic skin diseases, such as psoriasis and scabies. The plant is used to treat many diseases such as cough,cold diarrhea,inflammatory diseases. The leaves of the leucas aspera are linear, obtuse and are petiolate. Inhibition of naja naja venom enzymes by the methanolic. Four different crude extracts petroleum ether, chloroform, ethanol and water of leucas aspera spreng were investigated for antiinflammatory and analgesic activities in albino rats and mice, respectively at a dose of 400 mgkg body weight. Link is an accepted name this name is the accepted name of a species in the genus leucas family lamiaceae. It contains over 200 species, widespread over much of africa, and southern and eastern asia iran, india, china, japan, indonesia, etc. For more multimedia, look at leucas aspera on wikimedia commons. The result obtained shows that all the extracts expressed remarkable antifungal activity. Leucas aspera at gandipet, hyderabad, ap w img 9054. Leucas aspera nanomedicine shows superior toxicity and. Leucas aspera commonly known as thumbai has a wide variety of medical applications.
Using the patented highspeed transfer technology in ibm aspera, national instruments corporation was able to significantly accelerate its global software development pipeline by synchronizing large software builds between teams at 17 sites around the world from its centralized data center in austin, texas. Calyx tubular to obconical, rarely dilated, 10veined, straight or curved, truncate or oblique at throat, projected. Thus the new name for the family labiatae became lamiaceae. This file is licensed under the creative commons attributionshare alike 4. The crushed leaves are also used to treat mild fevers, colds, rheumatism and snake bites, and as a. Leucas aspera lamiaceae, an aromatic herbaceous plant, is well known for many medicinal properties and a number of bioactive compounds against animal cells have been isolated. Leucas aspera family labiatae is an annual herb found throughout india as a weed in cultivated fields, wastelands and roadsides. Green synthesis of silver nanoparticles using leucas aspera. Inhibition of cox2 enzyme by the various extracts of leucas. Pharmacological and medicinal uses of achyranthes aspera 127 bronchoprotective activity. Bioactive components have been isolated such as lignin,flavonoids, coumarins, steroids. Acetone extracts of leucas aspera roots showed excellent antibacterial activity against the tested bacterial strains.
Caryophyllene and 1octen3ol chemotypes, journal of chromatographic science on deepdyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips. The synthesized nanoparticles were characterized by using uv. Devi rajeswari department of biomedical sciences, school of biosciences and technology, vit university, vellore 14, tamilnadu, india. Pdf leucas aspera commonly known as thumbai is distributed throughout india from the himalayas down to ceylon. Microbiological activities of volatile constituents of leucas aspera. However, the name labiatae is also exempted and conserved under nomina conservanda because of their constant use for a long time. Although the species has many different common names depending on the region in which it is located, it is most commonly known as thumbai or thumba. Medicinally, it has antimicrobial, insecticidal, fever reducing, larvicidal and inflammation reducing properties. Floral formula and floral diagram biology discussion.
An update of leucas aspera a medicinal plant international. All structured data from the file and property namespaces is available under the creative commons cc0 license. The decoction of whole plant is used for curing fever. It is easy to id leucas when you have a live specimen with flower in hand otherwise it is difficult unless one worked on it. In india and the philippines leucas aspera is very common weed. Leaves are subsessile or shortly petiolate, linear or linearly lanceolate, obtuse, pubescent up to 8.
Leucas aspera is an annual plant that can reach heights of 1560 cm. The record derives from wcsp which reports it as an accepted name record 111632 with original publication details. Leucas aspera nanomedicine shows superior toxicity and cell. Leucas revealed the presence of tannins, alkaloids and glycosides ramya et al. Leucas aspera material was collected from gangapur dam, nasik, maharashtra, india. Leucas aspera is a plant species within the genus leucas and the family lamiaceae. The present object focuses on phyto constituents and antiangiogenic activity of the leucas aspera leaves extract. Calyx tubular to obconical, rarely dilated, 10veined, straight or curved, truncate or oblique at throat. Tlc is a good technique to analyze the compound of a. Antioxidant and antibacterial activity of different parts of leucas aspera.
Files are available under licenses specified on their description page. Lamiaceae herb rainy 23 gamhair pump, gamhair gmelina arborea roxb. Investigation of the inhibitory fraction of leucas aspera on prostaglandininduced contraction in guinea pig ileum provided four new diterpenes, leucasperones a 1 and b 2 and leucasperols a 3 and b 4, and three new isopimarane glycosides, leucasperosides a, b, and c 5. This study was aimed to develop an efficient protocol for micropropagation of leucas aspera using nodal explants. The aim of the present study is to probe the antimicrobial activities of methanol leaf extract of leucas sp. Home free radicals and antioxidants, vol 7, issue 2, juldec, 2017 phytochemical evaluation and in vitro antioxidant activity of various solvent extracts of leucas aspera willd. The relative density of most of weeds in cultivated fields the relative density of most of weeds in cultivated fields were 2. Ethanolic extract of achyranthes aspera shows bronchoprotective effect in toluene diisocyanate tdi induced occupational asthma in wistar rats as reported by goyal et al. Thin layer chromatographic investigation on leave of.
Phytochemical evaluation and in vitro antioxidant activity of. Neuropharmacological profile of methanolic extract of. It is annulate in the middle portion and pubescent on the upper region. In thin layer chromatography tlc, a liquid the mobile phase is allowed to migrate across a solid stationary phase15. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 111632 with original publication details. Apr 17, 2020 a few uploads earlier identified as leucas cephalotes anti bacterial activity of leucas aspera leaf extract against micrococcus pyogenes and escheria coli have also been reported rastogi and mehrotra details of some important contributors. Leucas aspera is typically found in dry, open, sandy soil and is abundant in areas with waste. The hydrodistilled essential oil was obtained from the aerial parts of l.
The healing properties of plants has been transferred within the human communities for over the centuries. This file contains additional information such as exif metadata which may have been added by the digital camera, scanner, or software program used to create or digitize it. The genus leucas includes about 100 asiatic and african species. Pdf two novel phytotoxic substances from leucas aspera. Traditionally, this species is taken orally for analgesic, antiinflammatory, antibacterial and wound healing treatments. Leucas aspera belongs to the family lamiaceae commonly known.
Specifically, we assessed the improved anticancer activity of leucas aspera nanoparticles compared with methanolic crude extract in pc3 prostate cancer cells and normal cells. Phytochemical evaluation and in vitro antioxidant activity. Link lamiaceae is an annual, branched herb used in traditional medicine as an antipyretic and insecticide. Molecular docking studies of phytochemicals from leucas aspera targeting escherichia coli and bacillus subtilis subcellular proteins. If the file has been modified from its original state, some details such as the timestamp may not fully reflect those of the original file. The purpose of this present study was to investigate the central nervous system cns depressant activities of methanolic extract of. The juice of the leaves is used as remedies for psoriasis, chronic. The plants have been reported to have antiinflammatory, analgesic, antidiarrheal, antimicrobial, antioxidant, and insecticidal activities. Antifungal susceptibilities of certain clinically isolated dermatophytes to methanol extracts of leucas aspera and leucas zeylanica leaves were performed using agar well diffusion method. Methanolic extract of leucas aspera was evaluated, in vitro, for its ability to inhibit the major enzyme activities of naja naja venom including protease, phospholipase a 2, hyaluronidase and hemolytic factors. Jcprc5 222 phytochemical studies on leucas aspera latha. Leucas aspera is a plant which is seen on waste land and roadsides of india. Academic sciences asian journal of pharmaceutical and.
Diterpenes from leucas aspera inhibiting prostaglandin. There is an increasing commercial demand for nanoparticles due to their wide applicability in various areas such as electronics, catalysis, chemistry, energy, and medicine. Antioxidant, antibacterial and cytotoxic effects of the. Plant details information about leucas aspera plant. The present finding suggests that the methanol root extract of l. In vitro studies on antibacterial, antifungal, and. Verticillasters few to many flowered, widely spaced, uniform or reduced in size at end of branches.
Leucas aspera commonly known as thumbai, gumma is found all over india. General information leucas aspera is an erect, annual plant with a muchbranched stem 30 60cm tall. It belongs to family labiatae and its scientific name is phlomis. Leucas aspera is commonly found throughout india and the philippines as well as the plains of mauritius and java. Department of pharmacy, international islamic university chittagong, chittagong4203, bangladesh. Home pharmacogn j, vol 11, issue 2, marapr, 2019 molecular docking studies of phytochemicals from leucas aspera targeting escherichia coli and bacillus subtilis subcellular proteins. Narasimhan, centre for floristic research, department of botany, madras christian college, tambaram. The plant is used for the treatments of antipyretic, antirheumatic, antiinflammatory, and antibacterial diseases. Phytochemical and pharmacological investigation of an indigenous medicinal plant leucas aspera v. Leucas aspera a perfect poor man remedy journal of. Department of agriculture agricultural research service. Leucas is a genus of plants in the family lamiaceae, first described by robert brown in 1810. It is sometimes found convenient to describe a flower by a simple and concise formula known as the floral formula.
Phytol a chemical constituent of leucas aspera through. Jul 09, 2019 antimicrobial activity of leucas aspera pdf both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. The below mentioned article provides a study note on the floral formula and the floral diagram. Antimicrobial activity of leucas aspera pdf both the extracts exhibited a significant antibacterial activity against all the screened microorganisms. Aqueous extract showed potent inhibitory activities against eac cells procreation in invivo. The aqueous and alcoholic extracts of leucas aspera were investigated for their action on experimental inflammation and on mast cell degranuatlion. Home free radicals and antioxidants, vol 7, issue 2, juldec, 2017 phytochemical evaluation and in vitro antioxidant activity of various solvent extracts of leucas aspera.
Molecular docking studies of phytochemicals from leucas. Then the remaining marc was successively extracted with ethyl. Jun 30, 2015 the genus leucas includes about 100 asiatic and african species. Although dronpushpi is a problematic weed for farmers, it is a tasty potherb for many rural people and a valuable medicinal herb for herbalists and is cultivated for.
Verbenaceae tree spring 24 guma arxa, choti guma leucas cephalotes spreng. Antiangiogenic and proapoptotic activity of aqueous extract. Leucas aspera is widely use d as foods and also for nutr itional requirement in countryside which was reported to have high protein content of 21. In vitro micropropagation and comparative free radical. Leucas aspera at gandipet, hyderabad, ap w2 img 9054. According to the rules of icbn the names of the families should end in aceae. Leucas aspera is used by rural and tribal population in assam in various problems like dysentery, diarrhea, sinusitis, headache, tonsil etc 814. Leucas aspera in the germplasm resources information network grin, u. Both the extracts exhibited significant antiinflammatory action of acute and chronic inflammation. Leucas aspera is one of the herbs found momentous due to its overriding medicinal outcomes. Leucas aspera is an annual, branched, herb erecting to a height of 1560 cm with stout and hispid acutely quadrangular stem and branches. Pharmacognostical evaluation of leucas aspera link. In vitro studies on antibacterial, antifungal, and cytotoxic. Lamiaceae herb rainy 25 gundru arxa, gundri sag alternanthera sessilis linn.